{"id":36371,"date":"2025-03-12T09:17:32","date_gmt":"2025-03-12T09:17:32","guid":{"rendered":"https:\/\/www.etap-lab.com\/?p=15255"},"modified":"2026-04-15T22:50:04","modified_gmt":"2026-04-15T20:50:04","slug":"technical-note-high-content-imaging-of-brain-on-chip-microfluidic-devices-using-preciscan-intelligent-acquisition","status":"publish","type":"ressource","link":"https:\/\/www.etap-lab.com\/en\/ressource\/technical-note-high-content-imaging-of-brain-on-chip-microfluidic-devices-using-preciscan-intelligent-acquisition\/","title":{"rendered":"Technical Note: High-content imaging of brain-on-chip microfluidic devices using PreciScan intelligent acquisition."},"content":{"rendered":"<p><!--ScriptorStartFragment--><\/p>\n<div class=\"scriptor-paragraph\"><span style=\"color: #0000ff;\"><strong>Brain-on-chips (BoC)<\/strong><\/span> are <strong>innovative tools<\/strong> that simulate complex brain environments, enhancing our <strong>understanding of neurodegenerative diseases (NDDs)<\/strong>. While a range of BoC platforms have been developed to model diverse NDD pathophysiologies, the various channel architectures of <span style=\"color: #0000ff;\"><strong>these microfluidic devices present challenges in image acquisition and analysis<\/strong><\/span>. High-content imaging <strong>protocols must be adaptable<\/strong> to these differing designs.<\/div>\n<p>&nbsp;<\/p>\n<div class=\"scriptor-paragraph\">This Technical Note, developed by Revvity in collaboration with ETAP-Lab, demonstrates <strong>an automated image acquisition protocol for BoC microfluidic devices<\/strong>. The protocol utilizes the Operetta CLS\u2122 high-content analysis system with PreciScan intelligent acquisition to effectively image neuronal cells in NETRI microfluidic devices.<\/div>\n<div><\/div>\n<div><\/div>\n<div class=\"scriptor-paragraph\">Key highlights:<\/div>\n<ul class=\"\">\n<li class=\"scriptor-listItemlist!list-1406cb37-293f-4c0b-9f3d-8392889333f00\">How to automate image acquisition of microfluidic devices<\/li>\n<li class=\"scriptor-listItemlist!list-1406cb37-293f-4c0b-9f3d-8392889333f00\">How to set up a pre-scan re-scan routine for selected relevant channels within brain-on- chip devices<\/li>\n<li class=\"scriptor-listItemlist!list-1406cb37-293f-4c0b-9f3d-8392889333f00\">How to increase throughput for quantitative microscopy-based screening of brain-on-chip models<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><strong><a href=\"mailto:marketing@etap-lab.com\">Contact our team<\/a> if you would like proof-of-concept on your therapeutics using a compartmentalized microfluidic device with our protocols and expertise. <\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>Download the Technical Note: <a href=\"https:\/\/www.revvity.com\/fr-en\/content\/high-content-imaging-brain-chip-microfluidic-devices-using-preciscan-intelligent\"><span role=\"link\">https:\/\/www.revvity.com\/fr-en\/content\/high-content-imaging-brain-chip-microfluidic-devices-using-preciscan-intelligent<\/span><\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<div>\n<div class=\"scriptor-paragraph\"><a href=\"https:\/\/www.revvity.com\/fr-en\/content\/high-content-imaging-brain-chip-microfluidic-devices-using-preciscan-intelligent\"><span role=\"link\"><!--ScriptorEndFragment--><\/span><\/a><\/div>\n<\/div>\n<p><!--ScriptorEndFragment--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Discover Technical Note: High-content imaging of brain-on-chip microfluidic devices using PreciScan intelligent acquisition.: Brain-on-chips (BoC) are innovative tools that simulate\u2026<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false},"categorie-de-ressource":[238],"marque-de-ressource":[],"class_list":["post-36371","ressource","type-ressource","status-publish","hentry","categorie-de-ressource-technical-notes"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - 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