{"id":36378,"date":"2025-09-16T10:34:29","date_gmt":"2025-09-16T10:34:29","guid":{"rendered":"https:\/\/www.etap-lab.com\/?p=15958"},"modified":"2026-04-28T17:09:59","modified_gmt":"2026-04-28T15:09:59","slug":"poster-pro-healing-effects-plasanaone-esdr2025","status":"publish","type":"ressource","link":"https:\/\/www.etap-lab.com\/en\/ressource\/poster-pro-healing-effects-plasanaone-esdr2025\/","title":{"rendered":"POSTER: &#8220;Pro-healing effects of Plasana One\u00ae, an argon-generated cold plasma on ischemic skin wounds\u201d"},"content":{"rendered":"\n<p>Discover the excellent results on ischemic skin wounds in our Poster: <strong>&#8220;Pro-healing effects of Plasana One\u00ae, an argon-generated cold plasma on ischemic skin wounds\u201d.<\/strong><br>\nPresented by Jean-Fran\u00e7ois Bisson at the European Society for Dermatological Research (<a href=\"https:\/\/esdrmeeting.org\/exhibitors\/\" target=\"_blank\" rel=\"noopener\">ESDR 2025<\/a>, Antwerp, Belgium), featuring results from a client study on our ischemic skin wound model, conducted in collaboration with \u00c9cole Polytechnique, Laboratoire de Physique des Plasmas &amp; Plasana M\u00e9dical.<\/p>\n\n\n\n<p>\u00a0\ud83d\udca1This study contributed to the preclinical development of the <a href=\"https:\/\/plasana-medical.com\/en\/\" target=\"_blank\" rel=\"noopener\">Plasana One\u00ae technology<\/a>, an innovative device which is now entering clinical trials, designed to efficiently treat chronic wounds such as venous leg ulcers and diabetic foot ulcers.<\/p>\n\n\n\n<p><a href=\"mailto:marketing@etap-lab.com?subject=Poster%20Request%20ESDR2025%20ETAP-Lab&amp;body=Hello,%0ACan%20you%20send%20me%20the%20poster%20dealing%20with%20wound%20healing%20research%20at%20ESDR2025.%20Thank%20you.\">EASY POSTER REQUEST<\/a><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>&nbsp;<\/p>\n\n\n\n<p><strong>Authors<\/strong>: J.-F. Bisson1 , L. Razafitrimo1 , L. Ogikian1 , R. Da Silva2,3 , P.-M. Fran\u00e7ois3 , Y. Matton3 , A. Rousseau2<\/p>\n\n\n\n<p><strong>Affiliations<\/strong>:<\/p>\n\n\n\n<p>1ETAP-Lab, D\u00e9partement de Dermatologie, Vandoeuvre-l\u00e8s-Nancy, France<br>\n2Ecole Polytechnique, Laboratoire de Physique des Plasmas, CNRS, Palaiseau, France<br>\n3Plasana M\u00e9dical, Boulogne-Billancourt, France<\/p>\n\n\n\n<p>&nbsp;<\/p>\n\n\n\n<p><strong>Abstract<\/strong>: Ischemic ulcers are chronic wounds that occur due to reduced blood flow and are characterized by their inability to heal within an expected time frame. Cold atmospheric plasma (CAP) has emerged as a promising non-invasive therapy capable of enhancing wound healing. Plasana One\u00ae is a medical device manufactured by Plasana Medical, based on an argon plasma quadrijet. On contact with the ambient air, CAP creates reactive chemical species of oxygen and nitrogen such as nitric oxide, known to promote healing. The purpose of the study was to evaluate the pro-healing effects of Plasana One\u00ae on experimental ischemic skin wounds. The four jets of Argon-generated cold plasmas were applied under anesthesia 3 times per week during 0 (untreated), 20 or 120 seconds on and around 26 mm diameter induced ischemic skin wounds on the back of rats, until complete healing. Both treatment durations led to a significantly faster and more pronounced production of granulation tissue, followed by a more rapid decrease compared to untreated rats. No signs of maceration were observed throughout the study on wounds of cold plasma treated rats unlike untreated rats. Both treatment durations resulted in a significantly faster healing compared to untreated rats (68.0\u00b15.3, 34.2\u00b12.9, 32.4\u00b11.9 and days for durations of 0, 20, 120 seconds respectively). Histological and immunohistochemical analyses of healed wounds showed that CAP treatments resulted in a more mature, thinner, well-organized, and differentiated neo-epidermis, as well as a more advanced stage of dermal scar tissue maturation, less inflammation, and greater neovascularization (number and size of newly formed blood vessels), with no difference between the two treatment durations. Hematological, blood biochemical and histological analyses of the main organs of cold plasma treated rats showed no significant difference compared to untreated rats.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Discover POSTER: &#8220;Pro-healing effects of Plasana One\u00ae, an argon-generated cold plasma on ischemic skin wounds\u201d: Discover the excellent on ischemic skin wounds in our Poster:\u2026<\/p>\n","protected":false},"featured_media":37803,"template":"","meta":{"_acf_changed":false},"categorie-de-ressource":[236],"marque-de-ressource":[],"class_list":["post-36378","ressource","type-ressource","status-publish","has-post-thumbnail","hentry","categorie-de-ressource-posters"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>POSTER: &quot;Pro-healing effects of Plasana One\u00ae, an argon-generated cold plasma on ischemic skin wounds\u201d - ETAP-LAB<\/title>\n<meta name=\"description\" content=\"Discover the excellent results on ischemic skin wounds in our Poster: &quot;Pro-healing effects of Plasana One\u00ae, an argon-generated cold plasma on ischemic skin wounds\u201d.Presented by Jean-Fran\u00e7ois Bisson at the European Society for Dermatological Research (ESDR 2025,)... featuring results from a client study on our ischemic skin wound model, conducted in collaboration with \u00c9cole Polytechnique, Laboratoire de Physique des Plasmas &amp; Plasana M\u00e9dical.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.etap-lab.com\/en\/ressource\/poster-pro-healing-effects-plasanaone-esdr2025\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"POSTER: &quot;Pro-healing effects of Plasana One\u00ae, an argon-generated cold plasma on ischemic skin wounds\u201d - 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