EWMA: Presentation of the results of work we conducted for URGO laboratories
Preclinical research carried out in a rat skin healing model that has shown the efficacy of a sucrose octasulfate dressing (UrgoStart) will be presented at the EWMA Digital Congress - 18 and 19 November 2020. We were able to show that the accelerated healing achieved by use of the innovative UrgoStart dressings was linked to faster and denser reconstruction of the local vascular network, in comparison with control conditions in rats. These results, invaluable for URGO laboratories, have made it possible
Our tau oligomer toxicity – a new tool for drug screening
The toxicity of the tau oligomers produced by ETAP-Lab can be reversed by using BDNF on primary rat neuron cultures. BNDF applied at the same time as tau oligomers significantly and reproducibly reduced cell mortality. Incubation of cortical neurons with Tau monomers, TauO and TauO+BDNF. TauO decreased quite significantly cell viability (*; p<0.01), while monomers showed no neurotoxic effect. Incubation with BDNF significantly reversed TauO-induced neurotoxicity (#; p<0.01). Data are expressed as percent of vehicle (set at 100%) and represent the mean ± SD. (N=3, n=12). This tauopathy model is now
ETAP-Lab a is expanding and recruiting a new employee for STROK@LLIANCE
ETAP-Lab a is expanding and recruiting a new employee for STROK@LLIANCE: there is a new Laboratory technician – Research assistant position available at STROK@LLIANCE(Caen, FRANCE). Please find here the If you fit to this profile, please contact us at recruitment@etap-lab.com Un nouveau poste de technicien de laboratoire – assistant de recherche est ouvert chez STROK@ALLIANCE (Caen, FRANCE). La description du poste est disponible
Tau oligomer toxicity – our first data!
The new tau oligomers produced by ETAP-Lab show reproducible and dose-dependent toxicity on rodent primary neuron cultures. Promising and repeatedly replicated data show that tau oligomers exhibit dose-dependent toxicity that is not observed with equivalent monomer concentrations. At high concentrations, the oligomers completely destabilise the neurons, leading to a rapid mortality rate of 100%. Now that the main technical obstacles have been overcome, a validated model for pharmacological screening should be ready soon. The next step is to evaluate some reference compounds.
BIO Japan 2020
ETAP-Lab will be attending BIO-Japan 2020 as part of the Business France virtual French pavilion. We are delighted to have this unprecedented opportunity to reach out to the Japanese market. We will be at BIO Japan 2020 throughout, from 14 to 16 October. Our experts Dr. Jean-François Bisson (VP) and Dr. Nicolas Violle (CEO) will be there to introduce you to the laboratory's activities in preclinical Neurology, Dermatology and Nutrition-Health. Please feel free to contact us to schedule a video conference. We’re hoping
Let’s get back on track together!
Have your preclinical R&D projects fallen behind schedule during lockdown? Every industrial activity has been knocked sideways by the COVID-19 emergency - and healthcare R&D is no exception. Because we’ve been busy preparing the ground for the recovery ever since the start of lockdown, we are ready to support you as best we can in the intense catch-up period that is to come. Many of the studies we helped plan during lockdown are already under way. We are glad to see our customers
B2B meetings at BIO-Digital: A fast-paced week filled with opportunities!
Thanks to everyone we met - we really appreciated the quality of our interactions, and are as excited as ever to be working alongside you on your preclinical projects. Thanks also to Business France and CCI France, for supporting the export of innovative French biotechs and CROs.
Meet us at BIO-Digital, 8-12 june
ETAP-Lab will participate at Bio-Digital next 8-12 June. Our experts Dr. Jean-François BISSON (VP) and Dr. Nicolas Violle (CEO) will present ETAP-Lab’s services in the fields of preclinical Dermatology and Central Nervous System. Please feel free to reach out if you want to schedule a one-to-one meeting. Looking forward to meeting with you.
COVID-19: Business Continuity
We hope that you are not being too hard hit by the current crisis, and that you and your family and friends remain healthy. Like many others, we have reorganized our production schedule to ensure continuity of service while keeping our team safe. Although things may take a little longer, our team is standing by to conduct your studies to the high-quality standards that underpin our reputation. This period of uncertainty also offers an opportunity for us to reflect on our R&D
ETAP-Lab’s dermatology activity keeps growing: our first project with a US-based company
By entrusting development of its drug candidate to our expertise, a NASDAQ-listed North American company is following the lead of European and Asian businesses by choosing ETAP-Lab’s DNCB-induced atopic dermatitis mouse model. Indeed, ETAP-Lab has just signed a major contract to assess the effects of a dermatological pharmaceutical treatment currently in development. Atopic dermatitis is a common skin condition that mainly results in redness, lesions and intense itching (pruritus). For patients, it can affect everyday life severely enough to cause anxiety and