Publications

EXPLORE OUR SCIENTIFIC RESOURCES

Contact an expert

Published on the 27 October 2014

Skin Repair Properties of d-Limonene and Perillyl Alcohol in Murine Models

The orange-peel derived terpene d-Limonene, probably through its metabolite, perillyl alcohol (POH), has been reported to have tissue-repair properties. Two murine models of respectively 12-O-Tetradec…
Published on the 15 October 2014

Anti-stress effects of d-Limonene and its metabolite perillyl alcohol

Stress is closely linked by its biological mechanisms to inflammation and by its consequences to accelerated aging. Stress triggers a hormonal response along the hypothalamus-pituitary-adrenal (HPA) a…
Published on the 24 July 2014

Preventive effects of lignan extract from flax hulls on experimentally induced benign prostate hyperplasia

Consumption of diet rich in lignans may decrease the risk of some chronic hormonal conditions such as benign prostatic hyperplasia (BPH). This study investigated whether a lignan-rich extract from fla…
Published on the 24 June 2014

Methylphenidate-risperidone combination in child psychiatry: A retrospective analysis of 44 cases

INTRODUCTION: Psychotimulant-antipyschotic combinations are frequently used in child psychiatry, but have been rarely described in the literature. METHOD AND PATIENTS: We propose here a retrospecti…
Published on the 24 March 2014

p-Coumaric acid activates the GABA-A receptor in vitro and is orally anxiolytic in vivo.

The increasing prevalence and social burden of subclinical anxiety in the western world represents a significant psychosocial and financial cost. Consumers are favouring a more natural and nonpharmaco…
Published on the 16 December 2013

Structure- Activity Relationship Study and Function-Based Petidomimetic Design of Human Opiorphin with Improved Bioavailability Property and Unaltered Analgesic Activity

Human opiorphin inhibits enkephalin-inactivating ectopeptidases to produce analgesic and antidepressant-like effects in standard murine models via activation of µ and/or δ opioid pathways. It is an en…
Published on the 1 July 2013

Oral administration of d-limonene controls inflammation in rat colitis and displays anti-inflammatory properties as diet supplementation in humans

AIMS: To further explore the anti-inflammatory properties of d-Limonene. MAIN METHODS: A rat model was used to compare evolution of TNBS (2,5,6-trinitrobenzene sulfonic acid)-induced colitis …
Published on the 28 June 2013

Mining the brain metabolome to understand behavioural disruptions induced in mouse fed Hypochoeris radicata (L.), a neurotoxic plant for horse

Mining the brain metabolome to understand behavioural disruptions induced in mouse fed Hypochoeris radicata (L.), a neurotoxic plant for horse. C57BL/6J mice orally exposed to 9% H. radicata (HR) are …