Syncrosome Cardiovascular Service Offering

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Our in vitro and in vivo models

SYNCROSOME offers a range of animal models for cardiovascular, cardiometabolic, cardiopulmonary, and thrombotic diseases, as well as several in vitro coagulation and fibrinolysis tests on human blood. Discover our preclinical pharmacology services for evaluating your drug candidates and medical devices.

OUR IN VITRO MODELS
OUR IN VIVO MODELS
16
rodent models
with integrated metabolic disorders and comorbidities
+450
tested molecules
extensive expertise in in vivo studies
+25
years of expertise
in modeling cardiovascular diseases
+1000
in vivo studies
on our rodent disease models
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Discover our platforms dedicated to supporting your studies

Our team of experts conducts your preclinical efficacy studies in a state-of-the-art environment to ensure robust, high-quality, and repeatable results.

SYNCROSOME integrates advanced technologies for translational research.

high content imaging results neurology

High-Content Imaging

ETAP-LAB provides a wide range of morphological and functional readouts within complex cellular models through High-Content Imaging technologies. Using the Operetta CLS™ platform (Revvity), we automate medium‑throughput fluorescence imaging and integrate AI‑enhanced image‑analysis pipelines to deliver rapid, high‑accuracy quantification of large datasets. Entrust your screening and lead-optimization campaigns to an expert team.
high content imaging of in vitro results

Brain‑on‑Chip platform

For several years, ETAP‑LAB has been investing in R&D programs aimed to engineer and scale-up brain‑on‑chip platforms, contributing to their routine adoption in preclinical CNS pharmacology. Built on compartmentalized microfluidic architectures, our brain‑on‑chip systems recreate the connectivity between spatially distinct neuronal populations maintained in different controlled microphysiological environments. This approach overcomes key limitations inherent to […]
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Small and Large Animal Facilities

ETAP‑LAB operates 1,000 m² of fully accredited facilities (A1/A2 level), distributed across three sites with a total housing capacity of approximately 1,200 rodents. Our facilities are also authorized for Class 1 genetically modified mice and immunodeficient strains (NUDE and humanized). Each facility includes controlled‑environment housing rooms, dedicated zootechnical areas, microsurgery platforms, and experimental rooms fully […]
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Preclinical Medical Imaging

Through our long‑standing partnership with the CYCERON imaging platform in Caen, located directly next to our facilities, we have privileged access to state‑of‑the‑art medical imaging tools within an internationally recognized infrastructure. ETAP‑LAB teams – trained, autonomous, and experienced – routinely use the following systems: A 7T MRI for high‑resolution anatomical and functional imaging in rodents, […]
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Immunohistochemistry, Immunofluorescence, and Histology

Our fully integrated IHC, immunofluorescence, and histology platform manages the entire workflow – from tissue collection to data interpretation – ensuring coordination with our in vivo platform and preserving sample integrity throughout. This end-to-end know-how enables reduced turnaround times and reliable analyses across a panel of pre-validated biomarkers. We process frozen tissues, including cryo‑embedding and […]
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Immunoassays

Our integrated immunoassay platform ensures a continuous workflow coordinated with our in vitro and in vivo platforms, enabling uncompromised sample integrity, shortening timelines, and delivering reliable analyses across a panel of prevalidated biomarkers. We routinely perform protein and enzymatic‑activity quantification using standardized colorimetric, fluorescent, and luminescent detection methods accross multiple sample types, including tissues, biological […]

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Our mission

Accelerate and secure your pipeline with premium preclinical services.

SYNCROSOME conducts preclinical pharmacology studies combining CRO‑level industrial standards with the scientific expertise of a research laboratory. We offer a full range of in vivo services, from standard to customized studies: lead optimization, POC, PK/PD, biomarker discovery, to meet your specific needs. We have three main areas of expertise to support your developments: right‑heart diseases (pulmonary hypertension), left‑heart diseases (myocardial infarction, HFpEF), and thrombotic diseases.

WORKING WITH ETAP‑LAB
Cardiovascular – plateforme vivo animalerie photo

OUR BRANDS

SYNCROSOME

Founded 35 years ago with recognized expertise in neurology, ETAP‑LAB has gradually expanded into other therapeutic areas. With the integration of the CRO SYNCROSOME into our activity in 2023, we now rely on over 25 years of expertise to conduct preclinical pharmacology studies in cardiology.

Our history

A SOCIETAL CHALLENGE

SYNCROSOME, a partner in cardiovascular health innovation.

Cardiovascular diseases remain the leading cause of mortality worldwide and continue to rise with the increasing prevalence of metabolic disorders (diabetes, obesity, hypertension). Heart failure, myocardial ischemia, and pulmonary hypertension are complex diseases for which therapeutic options remain limited. In response to this major health challenge, pharmaceutical companies pursue efforts to design and develop new therapeutic approaches capable of significantly improving patient care.
The SYNCROSOME team brings its expertise and platforms to support your innovation programs targeting cardiovascular diseases.

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Translational models
Supported by clinically relevant readouts
+25
years of expertise
A team dedicated to preclinical pharmacology
HFpEF models
To address cardiometabolic model needs
Mastered studies
Reproducible and validated with reference molecules