Brainxplore Neurology Service Offering

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Our in vitro and in vivo models

BRAINXPLORE offers a wide range of validated cellular and animal models in neurology and psychopharmacology. Discover our service offering in preclinical CNS pharmacology.

OUR IN VITRO MODELS
OUR IN VIVO MODELS
14
in vitro models
based on primary cells and human cells (hiPSCs)
+1000
in vivo studies
on our rodent disease models
7
animal models
in rodents with integrated risk factors
+300
clients worldwide
Biotechs and pharmaceutical companies
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Discover our platforms dedicated to supporting your studies

Our team of experts conducts your preclinical efficacy studies in a state-of-the-art environment to ensure robust, high-quality, and repeatable results.

BRAINXPLORE integrates cutting-edge technologies for translational research.

high content imaging results neurology

High-Content Imaging

ETAP-LAB provides a wide range of morphological and functional readouts within complex cellular models through High-Content Imaging technologies. Using the Operetta CLS™ platform (Revvity), we automate medium‑throughput fluorescence imaging and integrate AI‑enhanced image‑analysis pipelines to deliver rapid, high‑accuracy quantification of large datasets. Entrust your screening and lead-optimization campaigns to an expert team.
high content imaging of in vitro results

Brain‑on‑Chip platform

For several years, ETAP‑LAB has been investing in R&D programs aimed to engineer and scale-up brain‑on‑chip platforms, contributing to their routine adoption in preclinical CNS pharmacology. Built on compartmentalized microfluidic architectures, our brain‑on‑chip systems recreate the connectivity between spatially distinct neuronal populations maintained in different controlled microphysiological environments. This approach overcomes key limitations inherent to […]
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Small and Large Animal Facilities

ETAP‑LAB operates 1,000 m² of fully accredited facilities (A1/A2 level), distributed across three sites with a total housing capacity of approximately 1,200 rodents. Our facilities are also authorized for Class 1 genetically modified mice and immunodeficient strains (NUDE and humanized). Each facility includes controlled‑environment housing rooms, dedicated zootechnical areas, microsurgery platforms, and experimental rooms fully […]
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Preclinical Medical Imaging

Through our long‑standing partnership with the CYCERON imaging platform in Caen, located directly next to our facilities, we have privileged access to state‑of‑the‑art medical imaging tools within an internationally recognized infrastructure. ETAP‑LAB teams – trained, autonomous, and experienced – routinely use the following systems: A 7T MRI for high‑resolution anatomical and functional imaging in rodents, […]
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Immunohistochemistry, Immunofluorescence, and Histology

Our fully integrated IHC, immunofluorescence, and histology platform manages the entire workflow – from tissue collection to data interpretation – ensuring coordination with our in vivo platform and preserving sample integrity throughout. This end-to-end know-how enables reduced turnaround times and reliable analyses across a panel of pre-validated biomarkers. We process frozen tissues, including cryo‑embedding and […]
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Immunoassays

Our integrated immunoassay platform ensures a continuous workflow coordinated with our in vitro and in vivo platforms, enabling uncompromised sample integrity, shortening timelines, and delivering reliable analyses across a panel of prevalidated biomarkers. We routinely perform protein and enzymatic‑activity quantification using standardized colorimetric, fluorescent, and luminescent detection methods accross multiple sample types, including tissues, biological […]

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Our mission

Accelerate and secure your pipeline with premium preclinical services.

BRAINXPLORE conducts preclinical pharmacology studies dedicated to Central Nervous System (CNS) disorders on your behalf, combining CRO‑level industrial standards with the scientific expertise of a research laboratory. We offer a complete range of services from cell to animal: lead optimization, POC, Neuro-PK, PK/PD, biomarker discovery, to meet your specific needs. We have three areas of expertise in Neurology: neurodegenerative diseases (Alzheimer’s, Parkinson’s), psychopharmacology (Anxiety, Depression, Cognition), and Stroke. All our models are customizable.

WORKING WITH ETAP-LAB
Neurology & CNS – cffafdcdeddaabc

OUR BRANDS

BRAINXPLORE

Founded 35 years ago with recognized expertise in neurology, ETAP-LAB has progressively expanded its activities to other therapeutic areas. BRAINXPLORE is the name we chose to embody and promote this historical expertise, which remains a major pillar of our activity today.

Our history

A SOCIETAL CHALLENGE

BRAINXPLORE contributes to the development of tomorrow’s therapies.

The discovery of treatments for neurodegenerative diseases and neurological disorders remains a major public health challenge. Despite continuous efforts, the pharmaceutical industry faces a clinical attrition rate exceeding 90%.
BRAINXPLORE team provides its unique know‑how and innovative models to help you bridge the translational gap.

CONTACT AN EXPERT
35
years of expertise
A team dedicated to preclinical neuropharmacology
MPS & NAM models
Organ-on-chips and hiPSC co‑cultures
Translational animal models
Innovative models and clinically relevant readouts
Top‑grade oligomers
Production of oligomers for our in vitro and in vivo proteinopathy models