Strok@lliance Neurovascular Service Offering

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Our in vitro and in vivo models

STROK@LLIANCE offers a wide range of translational models, from small to large animals, to meet your needs in preclinical efficacy pharmacology and non‑GLP safety. We also provide in vitro tests on human blood and neuronal cultures to identify your lead compounds and support their mechanism of action. Discover our full range of services dedicated to preclinical stroke pharmacology.

5
in vitro models
on human blood and rodent cortical neurons
8
animal models
in rodents and pigs with integrated comorbidities
+5000
MRI scans
on rodents over 5 years for our clients
+300
clients worldwide
Biotechs and pharmaceutical companies

STROK@LLIANCE is a partnership created to industrialize innovative models developed by the PhIND laboratory (UMRS 1237 INSERM/UniCaen) and make them accessible for routine studies within the only CRO with a team 100% dedicated to stroke.

Located next to the CYCERON biomedical imaging center and the BB@C institute, STROK@LLIANCE benefits from one of the most dynamic ecosystems in the world for stroke research.

More than a technology transfer, the partnership brings together a unique combination of expertise and technologies to offer the best of academic and private know‑how within a single service.

Discover our platforms dedicated to supporting your studies

Our team of experts conducts your preclinical efficacy studies in a state-of-the-art environment to ensure robust, high-quality, and repeatable results.

STROK@LLIANCE integrates cutting‑edge technologies for translational research.

high content imaging results neurology

High-Content Imaging

ETAP-LAB provides a wide range of morphological and functional readouts within complex cellular models through High-Content Imaging technologies. Using the Operetta CLS™ platform (Revvity), we automate medium‑throughput fluorescence imaging and integrate AI‑enhanced image‑analysis pipelines to deliver rapid, high‑accuracy quantification of large datasets. Entrust your screening and lead-optimization campaigns to an expert team.
high content imaging of in vitro results

Brain‑on‑Chip platform

For several years, ETAP‑LAB has been investing in R&D programs aimed to engineer and scale-up brain‑on‑chip platforms, contributing to their routine adoption in preclinical CNS pharmacology. Built on compartmentalized microfluidic architectures, our brain‑on‑chip systems recreate the connectivity between spatially distinct neuronal populations maintained in different controlled microphysiological environments. This approach overcomes key limitations inherent to […]
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Small and Large Animal Facilities

ETAP‑LAB operates 1,000 m² of fully accredited facilities (A1/A2 level), distributed across three sites with a total housing capacity of approximately 1,200 rodents. Our facilities are also authorized for Class 1 genetically modified mice and immunodeficient strains (NUDE and humanized). Each facility includes controlled‑environment housing rooms, dedicated zootechnical areas, microsurgery platforms, and experimental rooms fully […]
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Preclinical Medical Imaging

Through our long‑standing partnership with the CYCERON imaging platform in Caen, located directly next to our facilities, we have privileged access to state‑of‑the‑art medical imaging tools within an internationally recognized infrastructure. ETAP‑LAB teams – trained, autonomous, and experienced – routinely use the following systems: A 7T MRI for high‑resolution anatomical and functional imaging in rodents, […]
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Immunohistochemistry, Immunofluorescence, and Histology

Our fully integrated IHC, immunofluorescence, and histology platform manages the entire workflow – from tissue collection to data interpretation – ensuring coordination with our in vivo platform and preserving sample integrity throughout. This end-to-end know-how enables reduced turnaround times and reliable analyses across a panel of pre-validated biomarkers. We process frozen tissues, including cryo‑embedding and […]
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Immunoassays

Our integrated immunoassay platform ensures a continuous workflow coordinated with our in vitro and in vivo platforms, enabling uncompromised sample integrity, shortening timelines, and delivering reliable analyses across a panel of prevalidated biomarkers. We routinely perform protein and enzymatic‑activity quantification using standardized colorimetric, fluorescent, and luminescent detection methods accross multiple sample types, including tissues, biological […]

Scientific resources

Our mission

Transform your stroke-targeting innovations into therapeutic success.

STROK@LLIANCE conducts preclinical pharmacology studies dedicated to neurovascular and CNS disorders, combining CRO‑level industrial standards with the scientific expertise of a research laboratory. We offer a full range of services, from cell to large animal, including standard and customized studies: POC, PK/PD, non‑GLP safety, biomarker identification and monitoring. We address all your needs in preclinical evaluation of neurovascular and hemostasis‑related conditions.
We have four areas of expertise in stroke and acute CNS injury: in vitro screening on human blood, ischemic stroke, hemorrhagic stroke, and bleeding‑risk evaluation for therapies.

 

Neurovascular & Stroke – stk header main cresyl stroke

Stroke, the third leading cause of mortality and acquired disability worldwide, remains a major global health challenge. With 94 million people affected and 160 million DALYs in 2021, it still lacks truly effective therapeutic solutions.

STROK@LLIANCE provides next‑generation in vitro and in vivo models, combined with advanced imaging and analytical technologies, to accelerate identification and validation of a ground-breaking treatment for pharmacological management of stroke.

8
years of expertise
Unmatched know‑how in stroke modeling.
Translational imaging
Combined with behavioral studies and biomarker analysis
Scientific advisory
Pr. Denis Vivien (PU/PH), internationally recognized KOL
11.9 million
cases
Global incidence of stroke in 2021