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Published on the 1 October 2009

Variations in illumination, closed wall transparency and/or extramaze space influence both baseline anxiety and response to diazepam in the rat elevated plus-maze

Numerous methodological-related variables have been demonstrated to influence the baseline anxiety level of rodents exposed to the elevated plus-maze (EPM), raising questions about the sensitivity of …
Published on the 1 September 2009

Hippocampal-dependent spatial memory functions might be lateralized in rats: an approach combining gene expression proﬁling and reversible inactivation

The hippocampus is involved in spatial memory processes, as established in a variety of species such as birds and mammals including humans. In humans, some hippocampal-dependent memory functions may b…
Published on the 21 August 2009

Effects of a Bovine Alpha S1-Casein Tryptic Hydrolysate (CTH) on Sleep Disorder in Japanese General Population

This study describes the effect of bovine alpha-S1 casein tryptic hydrolysate (CTH) in a representative sample of day-time workers from the general population of Japan with the occurrence of insomnia …
Published on the 1 June 2009

Anxiolytic-like effects and safety profile of a tryptic hydrolysate from bovine alpha s1-casein in rats

The anxiolytic activity and adverse benzodiazepine-like effects of a bovine alpha s1-casein tryptic hydrolysate (CH) were evaluated. The effects of CH orally administered at doses of 5 and 15 mg/kg we…
Published on the 1 May 2009

An oligofructose-enriched inulin diet: cognitive and physical performances in rats

The aim of the present study was to investigate the effects of long-term intervention with oligofructose-enriched inulin on behavioral cognitive, and visuomotor coordination in rats. Three-month-old m…
Published on the 1 April 2009

Two acute psychotic episodes after administration of bupropion: a case of involuntary rechallenge

Bupropion is an antidepressant drug also used as a smoking cessation aid, which inhibits norepinephrine and dopamine re-uptake. Given its pharmacological properties, it has been associated with report…
Published on the 1 January 2009

Food dextrin protects against colonic inflamamtion and prevents cognitive impairments

The aim of the present study was to investigate the protective effects of the dextrin NUTRIOSE® 6 (Dex) on colonic inflammation. Five percent of Dex or Glucose (Glu) diets were administered for 2 week…
Published on the 1 January 2009

Effect of music therapy on anxiety and depression in patients with Alzheimer’s type dementia: randomised, controlled study

BACKGROUND/AIMS: Numerous studies have indicated the value of music therapy in the management of patients with Alzheimer's disease. A recent pilot study demonstrated the feasibility and usefulness …