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Published on the 1 September 2009

Hippocampal-dependent spatial memory functions might be lateralized in rats: an approach combining gene expression proﬁling and reversible inactivation

The hippocampus is involved in spatial memory processes, as established in a variety of species such as birds and mammals including humans. In humans, some hippocampal-dependent memory functions may b…

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Published on the 1 June 2009

Anxiolytic-like effects and safety profile of a tryptic hydrolysate from bovine alpha s1-casein in rats

The anxiolytic activity and adverse benzodiazepine-like effects of a bovine alpha s1-casein tryptic hydrolysate (CH) were evaluated. The effects of CH orally administered at doses of 5 and 15 mg/kg we…

Publications
Published on the 1 April 2009

Two acute psychotic episodes after administration of bupropion: a case of involuntary rechallenge

Bupropion is an antidepressant drug also used as a smoking cessation aid, which inhibits norepinephrine and dopamine re-uptake. Given its pharmacological properties, it has been associated with report…

Publications
Published on the 1 January 2009

Food dextrin protects against colonic inflamamtion and prevents cognitive impairments

The aim of the present study was to investigate the protective effects of the dextrin NUTRIOSE® 6 (Dex) on colonic inflammation. Five percent of Dex or Glucose (Glu) diets were administered for 2 week…

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Published on the 1 January 2009

Effect of music therapy on anxiety and depression in patients with Alzheimer’s type dementia: randomised, controlled study

BACKGROUND/AIMS: Numerous studies have indicated the value of music therapy in the management of patients with Alzheimer's disease. A recent pilot study demonstrated the feasibility and usefulness …

Publications
Published on the 1 December 2008

Antidepressant-like effects of a cocoa polyphenolic extract in Wistar-Unilever rats

Depression is a major public health problem affecting about 12% of the world population. Drugs exist but they have many side effects. In the last few years, natural substances (e.g. flavonoids) have b…

Publications
Published on the 1 November 2008

Impact of sugar replacers on cognitive performance and function in rats

Glycaemic responses to the dextrin NUTRIOSE 6 (Dex) and the MALTISORB maltitol (Mal) have been studied previously but their effects on vigilance and cognitive performances are still not known. The pre…

Publications
Published on the 1 July 2008

Effects of long-term administration of a cocoa polyphenolic extract (Acticoa powder) on cognitive performances in aged rats

Numerous studies have indicated that increased vulnerability to oxidative stress may be the main factor involved in functional declines during normal and pathological ageing, and that antioxidant agen…

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