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Published on the 1 December 2004

The endogenous androgen-regulated sialorphin modulates male rat sexual behavior

In sexually mature male rats, sialorphin is synthesized under androgenic control and its surge endocrine secretion is evoked in response to environmental acute stress. These findings led us to suggest…
Published on the 13 September 2004

Effects of different germination conditions on the contents of free protein and non-protein amino acids of commercial legumes

Seeds of beans, lentils and peas were germinated for 2, 4 and 6 days, either under continuous light or continuous dark, and the free amino acids analysed by HPLC. The effects of germination on the fre…
Published on the 1 July 2003

Sialorphin, a natural inhibitor of rat membrane-bound neutral endopeptidase that displays analgesic activity

Sialorphin is an exocrine and endocrine signaling mediator, which has been identified by a genomic approach. It is synthesized predominantly in the submandibular gland and prostate of adult rats in re…
Published on the 1 February 2003

The delivery rate of dietary carbohydrates affects cognitive performance in both rats and humans

RATIONALE: Glucose is the main metabolic fuel of the brain. The rate of glucose delivery from food to the bloodstream depends on the nature of carbohydrates in the diet, which can be summarized as …
Published on the 1 January 2003

Effects of ING-911, a tryptic hydrolysate from bovine Milk alpha S1-Casein on anxiety of Wistar male rats measured in the conditioned defensive burying paradigm and the elevated-plus maze test

ING-911 is a tryptic hydrolysate from bovine milk that contains as a major component, a peptide corresponding to the 91-100 fragment of the α S1-casein. As diazepam (DZ), ING-911 was found to have an …
Published on the 1 November 2002

A new method of implanting orthotopic rat bladder tumor for experimental therapies

We developed a model of orthotopic transplantation of bladder tumor cells in female Fischer rats using a new reproducible technique. After first performing the mechanical abrasion of a portion of the …
Published on the 1 September 2002

Determination of the maximal tumor:normal bladder ratio after i.p. or bladder administration of 5-aminolevulinic acid in Fischer 344 rats by fluorescence spectroscopy in situ

The two major steps in our study on the treatment of bladder tumors by photodynamic therapy (PDT) were the development of a new bladder tumor model in Fischer rats by implantation of tumor cells and t…
Published on the 1 September 2002

Induction of syngeneic intradermal and orthotopic epidermal carcinomas in hairless Skh-1 mice as a reproducible model for experiments

Epidermoid carcinomas, clinically and histologically similar to human squamous cell carcinomas (SCC), were obtained in hairless Skh-1 mice. Tumor cells originated from chemically-induced skin cancers….