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Published on the 1 July 2011

Neurobehavioral and physiological effects of low doses of polubrominated diphenyl ether (PBDE)-99 in male adult rats

Polybrominated diphenyl ethers (PBDEs) are flame retardants. Because of their high lipophilicity and persistence, PBDEs bioaccumulate in all abiotic and biological matrices. The aim of this study was …
Published on the 1 July 2011

Beneficial psychological effects of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in healthy human volunteers
Published on the 18 April 2011

Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions

The corollaries of the obesity epidemic that plagues developed societies are malnutrition and resulting biochemical imbalances. Low levels of essential n-3 polyunsaturated fatty acids (n-3 PUFAs) have…
Published on the 1 March 2011

Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects

In a previous clinical study, a probiotic formulation (PF) consisting of Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 (PF) decreased stress-induced gastrointestinal discomfort. Emer…
Published on the 1 January 2011

Efficacy of chronic antidepressant treatments in a new model of extreme anxiety in rats

Animal models of anxious disorders found in humans, such as panic disorder and posttraumatic stress disorder, usually include spontaneous and conditioned fear that triggers escape and avoidance behavi…
Published on the 1 August 2010

Systemically active human opiorphin is a potent yet non-addictive analgesic without drug tolerance effects

Human opiorphin QRFSR-peptide protects enkephalins from degradation by human neutral endopeptidase (hNEP) and aminopeptidase-N (hAP-N) and inhibits pain perception in a behavioral model of mechanical …
Published on the 1 June 2010

Human opiorphin is a naturally occurring antidepressant acting selectively on enkephalin-dependent delta-opioid pathways

Human opiorphin protects enkephalins from degradation by human neutral endopeptidase and aminopeptidase-N and inhibits pain perception in various behavioral rodent models of pain via endogenous enkeph…
Published on the 24 May 2010

Lesions to the ventral, but not the dorsal, medial prefrontal cortex enhance latent inhibition.

The acquisition of a conditioned response to a stimulus when it is paired with a reinforcer is retarded if the stimulus has previously been repeatedly pre-exposed in the absence of the reinforcer. Thi…